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Iranian forces say they have struck a American military facility in Manama, as Iran launched strikes across the region in response for a significant and ongoing attack against it by the United States and Israeli forces.

Large columns of dark smoke were observed billowing from an area near the command center of the US Navy's Fifth Fleet in Bahrain's capital, Manama. The extent of any impact is not yet known and the US has yet to issue a statement.

Missile Defenses Activated

Elsewhere across the region, the United Arab Emirates, Qatar and the State of Kuwait - each hosting US military bases - stated they have shot down incoming projectiles in their territorial skies.

In the Qatari capital, the Qatari Ministry of Defence said it had intercepted a number of projectiles seemingly aimed at the Al Udeid Air Base, the biggest US military installation in the region.

IRGC Statement

The Iranian Revolutionary Guard declared it was targeting American facilities and interests as part of military campaign "Truthful Promise 4", in response for the attack on Iran initiated by the US and Israel on Saturday.

That preceding assault - executed at approximately 09:15 Iran time - has so far focused on sites linked to the Iranian leadership, with US President Donald Trump encouraging the Iranian people to rise up against the leadership.

Regional Fallout

In the State of Israel, air raid sirens sounded nationwide after the Israel Defense Forces said it had detected an barrage of missiles from Iran.

The Ministry of Defence of the UAE said in a statement that the country has been targeted by a "a blatant attack involving Iranian ballistic missiles".

"UAE air defence systems responded to the projectiles with great effectiveness and shot down a number of missiles," it added.

It said missile fragments fell on a neighborhood in the capital, causing some property damage and killing a civilian.

The US Air Force operates from Al Dhafra Air Base, to the south of Abu Dhabi, along with the Emirati Air Force.